New supplement thread

i wanted to like this so bad… it’s bland, i wanted a lucky charm taste… it’s not there.

looks like a 10… taste like a 2.

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At least it’s not moo-ing

honestly is why i bought them, i legit wanted to say something good here… i even ripped a “cereal” piece out of it, which was soft like a marshmallow, but had no flavor, really disappointed.

texture is great, so there’s that.

Doug, GNC or VS?

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I will try at Arnold, but I have yet to have a Redcon1 product that truly has blown me away with taste. To be quite honest they market well, but underwhelm me with flavor.

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ordered off their site, had a 33% off code

hypertrophy33 (i think)

just got one bar of the 3 flavors

if the Cinnamon or fruity ones are any better, i’ll report back on them.

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It’s app33 now but I’ll try them either way. Worth a bar of each. Just ordered.

I tried to buy the outright bars a few days ago and the variety and new butterscotch was sold out.

Outright bars, are my far and away favorites… Nate and I both rave about them.

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That’s the only reason I am even considering them

Best protein snack on the market (Outright bars). Go into a box with ease.
I will be at TigerFtiness HQ tomorrow, maybe I can get you an ETA on a re-stock for the butterscotch.

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Nice. It’s that one and the PBOR that I am most interested in. So I figured I would buy a variety and a box of butterscotch since it’s probably not in the variety and getting the best reviews.

PB oatmeal raisin is my #2 behind Almond butter chocolate chip. I love oatmeal cookies and the peanut butter base is fantastic.

The almond butter base though… next level paired with the honey.

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it’s the GOAT dead srs

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Sorry to bump your bubble but I just gotta say it. The placebo is strong with this one.

Lipovate (Upgraded Shift)

so now its a GDA. eh

Seems like a kind of hybrid GDA/fat burner. Interesting, but still a Glycophase fan personally

I saw a post in Instagram a few days ago that talked about berberine reducing protein synthesis. If that study is legit, berberine would not be that good?

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At least in mice.
I kinda get it. Anything that reduced mTOR and increases autophagy would not stimulate muscle growth. However, those processes are also muscle-sparing. Not sure why berberine would increase atrophy, unless it’s different in humans than mice.

Here’s the study

OBJECTIVE:

Defects in insulin/IGF-1 signaling stimulate muscle protein loss by suppressing protein synthesis and increasing protein degradation. Since an herbal compound, berberine, lowers blood levels of glucose and lipids, we proposed that it would improve insulin/IGF-1 signaling, blocking muscle protein losses.

RESEARCH DESIGN AND METHODS:

We evaluated whether berberine ameliorates muscle atrophy in db/db mice, a model of type 2 diabetes, by measuring protein synthesis and degradation in muscles of normal and db/db mice treated with or without berberine. We also examined mechanisms for berberine-induced changes in muscle protein metabolism.

RESULTS:

Berberine administration decreased protein synthesis and increased degradation in muscles of normal and db/db mice. The protein catabolic mechanism depended on berberine-stimulated expression of the E3 ubiquitin ligase, atrogin-1. Atrogin-1 not only increased proteolysis but also reduced protein synthesis by mechanisms that were independent of decreased phosphorylation of Akt or forkhead transcription factors. Impaired protein synthesis was dependent on a reduction in eIF3-f, an essential regulator of protein synthesis. Berberine impaired energy metabolism, activating AMP-activated protein kinase and providing an alternative mechanism for the stimulation of atrogin-1 expression. When we increased mitochondrial biogenesis by expressing peroxisome proliferator-activated receptor gamma coactivator-1alpha, berberine-induced changes in muscle protein metabolism were prevented.

CONCLUSIONS:

Berberine impairs muscle metabolism by two novel mechanisms. It impairs mitochonidrial function stimulating the expression of atrogin-1 without affecting phosphorylation of forkhead transcription factors. The increase in atrogin-1 not only stimulated protein degradation but also suppressed protein synthesis, causing muscle atrophy.

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This is actually something I’ve been greatly interested by as well. Having glycogen shuttles to the muscle is great and all, but not at the expense of my body recovering and strengthening itself. I’ve cut back on my GDA use until I see further evidence supporting either side, after seeing this a few weeks ago. Once a every couple of days or strictly larger caloricly dense meals

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