I’ve heard before (but I’ve never verified) that kre-alkalyn is 97% creatine, leaving very little space for any real amount of buffering ingredient. I also know Dr. Golini has sued almost every researcher that’s published studies showing negative results on kre-alkalyn. Additionally, the concept of buffering creatine seems to be flawed. Most of the research I’ve seen shows creatine to be relatively stable in water. There’s also been an article on SuppVersity showing creatine is relatively stable at extremely low pH (<2). Therefore, if taken on an empty stomach, there should be no trouble taking monohydrate. Apparently stability goes down in the pH 3-4 range, which is often seen following meals, making creatine less optimal if taken with food. Given the minimal available space for buffering agents in kre-alkalyn, it could possibly (not conclusively) raise stomach pH into a range in which it actually breaks down faster. I’d stay away from kre-alkalyn, but if you are overly concerned with the pH, as others have said, throw in baking soda.
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