Hey this is a great comment and I'll just paste what I wrote in response to a similar comment in the other page:
"You're right, the HED from that study should be mentioned. We discuss the cost concerns here already and should have explained more deeply. But recall that we used to think you had to load 20g creatine every day for a week or so, turns out you don't. Human equivalent dose of a successful rat study doesn't mean it's the *only* acceptable dose.
So just like 3g creatine turned out to be fine, hopefully some smaller dosage of tomatidine will still show results too."
Either way, new ingredients are expensive, costs will eventually come down, but just because rats are having success at those large doses doesn't necessarily mean nothing will happen at less. We simply don't know.
New stuff's for those who are less conservative and have budget. I'd never tell anyone "You GOTTA spend $65 on this!"
But with that said, it's only fair to update the post ASAP